Myrtenol synthesis - by isomerisation of beta-pinene epoxide

摘要

Myrtenol is prepd. by isomerisation of beta-pinene epoxide in presence of strongly basic reagent. Basic reagent is selected from organo-metallic cpds., Al, Na, K, Li alcoholates, Na or Li mono- or di-alkyl amides. Pref. epoxide is prepd. by oxidn. of beta-pinene in basic medium by oxygenated water in presence of organic nitrile. Simple synthesis is selective and gives high yield.