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1-Amino substituted 1-cycloalkane derivatives of 7-aminocephalosporanic acid and 7-aminodesacetoxy cephalosporanic acid
1-Amino substituted 1-cycloalkane derivatives of 7-aminocephalosporanic acid and 7-aminodesacetoxy cephalosporanic acid
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机译:7-氨基头孢烷酸和7-氨基去乙酰氧基头孢烷酸的1-氨基取代的1-环烷烃衍生物
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摘要
Disclosed herein are novel compounds of the formula WHEREIN W is -CH3 or -CH2OCOCH3, m is 0, 1 or 2; R is alkyl of from 1 to 7 carbon atoms, hydroxy or halogen; n is 0, 1, 2 or 3; R1 is phenyl, naphthyl, substituted phenyl or naphthyl wherein the substituent is halogen, hydroxy, or alkyl, alkoxy or acyl, each of from 1 to 4 carbon atoms, or amido; and Z is hydrogen, alkyl of from 1 to 7 carbon atoms or a salt forming ion. These compounds, prepared by condensing a Schiff's base of a 1-amino-1-cycloalkane carboxylic acid with 7-ACA or 7-ADCA, are useful as antibacterial agents.
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