STREPTOMYCIN DERIVATIVE AND PROCESS FOR MANUFACTURE OF STREPTOMYCIN DERIVATIVE BY MUTATION BIOSYNTHESIS

摘要

A method of making new derivatives of streptomycin by mutational biosynthesis. A mutant of Streptomyces griseus makes streptomycin production dependent on streptidine addition.P PA new antibiotic, deoxystreptomycin, is disclosed.