DERIVATIVES OF STREPTOMYCIN AND METHOD OF PRODUCING STREPTOMYCIN DERIVATIVES BY MUTATIONAL BIOSYNTHESIS

摘要

ABSTRACT OF THE DISCLOSUREA method of making new derivatives of streptomycinby mutational biosynthesis. A mutant of Streptomyces griseusmakes streptomycin production dependent on streptidine addition.A new antibiotic, deoxystreptomycin, is disclosed.