PROCESS FOR PREPARATION CYCLIC PENTANE DERIVATIVES SIMILLAR TO PROSTAGLANDINE USED AS CONTRASEPTIVES AND AS HYPOTENSIVE VE

摘要

A prostanoic acid (I) or its salt, is new. A prostanoic acid of formula (I) or its salt, is new. R 1hydroxymethyl, carboxy radical or up to 11C alkoxycarbonyl radical; R 2hydroxy radical or 1-4C alkanoyloxy radical; R 3H, or may combine with R 2to form oxo radical; A : ethylene or trans-vinylene radical; X : 1-3C alkylene radical optionally containing 1-3C alkyl; Y' : oxygen, sulfur, sulfinyl (-SO-) or up to 4C alkylimino (-N-alkyl-) radical; and R 4aryl, benzyl or furfuryl radical (all optionally substituted by halo, hydroxy, nitro or phenyl radical), alkyl, alkenyl, halogenoalkyl, alkoxy, alkenyloxy or up to 4C acylamino radical or dialkylamino radical containing 1-3C alkyl. The compound optionally contains up to 4C alkyl radical on 2, 3 or 4 carbon atom. An independent claim is included for manufacture of the prostanoic acid. [Image] ACTIVITY : Muscular-Gen.; Contraceptive; Hypotensive. No biological data given. MECHANISM OF ACTION : None given.