首页> 外国专利> method for preparing pharmaceutical preparations with spasmolytische effect, thus formed pharmaceutical preparations.and method for preparation of 3 - (di - (2 - thienyl) methylideen) - n - methylpiperidinederivaten.

method for preparing pharmaceutical preparations with spasmolytische effect, thus formed pharmaceutical preparations.and method for preparation of 3 - (di - (2 - thienyl) methylideen) - n - methylpiperidinederivaten.

机译:制备具有痉挛作用的药物制剂的方法,由此形成药物制剂。和制备3-(二-(2-噻吩基)亚甲基)-n-甲基哌啶衍生物的方法。

摘要

Di-(2-thienyl)-(N-methyl-5-methoxy-3-piperidyl)-carbinol is dehydrated. Di-(2-thienyl)-(N-methyl-5-methoxy-3-piperidylidine-methane is produced. The resultant di-(2-thienyl)-(N-methyl-5-methoxy-3-piperidylidene)-methane is reacted with a compound of the formula R-X, wherein R is lower alkyl and X is an anionic residue of a pharmaceutically acceptable acid. A compound having the formula WHEREIN X and R are as defined above, is produced. This compound is a potent antispasmodic.
机译:将二-(2-噻吩基)-(N-甲基-5-甲氧基-3-哌啶基)-甲醇脱水。制备二-(2-噻吩基)-(N-甲基-5-甲氧基-3-哌啶基-甲烷),生成的二-(2-噻吩基)-(N-甲基-5-甲氧基-3-哌啶基)-甲烷化合物与式RX的化合物反应,其中R是低级烷基,X是药学上可接受的酸的阴离子残基,制备了式WHEREIN X和R如上定义的化合物,该化合物是有效的解痉剂。

著录项

  • 公开/公告号NL148897B

    专利类型

  • 公开/公告日1976-03-15

    原文格式PDF

  • 申请/专利权人 TANABE SEIYAKU CO. LTD. OSAKA JAPAN.;

    申请/专利号NL19710007961

  • 发明设计人

    申请日1971-06-10

  • 分类号C07D409/14;A61K31/445;

  • 国家 NL

  • 入库时间 2022-08-23 02:51:35

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