process for the preparation of d - gay steroi - den and method for the preparation of a drug on the basis of these steroids.

摘要

D-Homo-21-carboxylic acids of the formula IMAGE the represents a single bond or a double bond; X is a hydrogen atom, a fluorine atom, or methylene; Y is a hydrogen atom, a fluorine atom, or a chlorine atom; Z is methylene, carbonyl, beta -hydroxymethylene, a beta -alkanoyloxymethylene or when Y is a chlorine atom, also beta -fluoromethylene or beta -chloromethylene; R1 is a hydrogen atom or methyl; and R2 is a hydrogen atom, hydroxy or alkanoyloxy; and their physiologically acceptable salts with bases and the 21-esters thereof, possess topical anti-inflammatory activity.