SYNTHESIS OF QUINONE DERIVATIVES HAVING BIOLOGICAL ACTIVITY

摘要

A procedure for the synthesis of quinonic derivatives that have biological activity, represented by the formula: ** (See formula) ** wherein R1 and R2 are methoxy groups or together with the carbon atoms to which they are attached constitute a benzene ring, and R is a residue represented ** (See formula) ** zero (0) or an integer from 1 to 9 inclusive, and A and B are hydrogen atoms or together form a direct bond, characterized in that a -allyl-halogenated nickel complex compound represented by the formula: ** (See formula) ** where the Xs are halogen atoms, the Rs have the same meanings as above, and each of the bonds is marked with a single dotted line, .... represents a semi-bond, and each of the bonds marked with the solid and dotted lines, combined, ....., represents a semi-double bond, with a quinonic derivative represented by the general formula: ** (See formula) ** in which R1, R2 and X respectively, have the same meanings previously defined. (Machine-translation by Google Translate, not legally binding)