O-(NITROARYL)OXIMES OF 3-KETO STEROIDS

摘要

O-(Nitrophenyl)oximes of 3-keto steroids of formula (where z is a single or double bond; R1 and R2 are H or NO2, but not both H; R3 is H or Me; R6 is OH pt. esterified, keto or Ac; R4 is H, Me, Et or ethinyl; R5 is H or Me; R7 is H or halogen; R8 is H or halogen) have anabolic and androgenic activity. They control fertility in mammals when administered during or post coitus. They are prepared from a 3-ketosteroid (oxime).