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Enzyme-regulating and cardiovascular compsns - contg. acylated anilinobutyric acids eg to increase prodn. of pancreatic and gastric enzymes
Enzyme-regulating and cardiovascular compsns - contg. acylated anilinobutyric acids eg to increase prodn. of pancreatic and gastric enzymes
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机译:酶调节和心血管功能-续酰化的苯胺丁酸,例如增加产品。和胃酶的种类
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摘要
Compsn. for regulating gastrointestinal enzymes and having cardiovascular analeptic activity contains an acylated anilinobutyric acid of formula (I) (R1-R5=H, 1-4C alkyl, alkoxy or alkylthio, halo or CF3; R3 can alos be OH or PhCH20; Y= is not 6C alkyl or cycloalky or opt. substd. is not 16C aryl; Z=H or an equiv. of a salt-forming cation). Pref. cpds. have R1-R5=1-2C alkyl or alkoxy, Cl or CF3;R3 may also be OH or PhCH2O; Y=1-2c alkyl or phenyl opt. substd. by Cl; Z=H or an equiv. of Na, K, Ca, Mg, Al, glucosamine, N-methylglucosamine, mono-di-or-tri-ethanolamine or ethylenediamine.
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机译:Compsn。用于调节胃肠道酶并具有心血管止痛活性的化合物包含式(I)的酰化的苯胺丁酸(R1-R5 = H,1-4C烷基,烷氧基或烷硫基,卤素或CF3; R3可以是OH或PhCH20; Y =是不大于6C的烷基或环烷基或最佳取代基不大于16C的芳基; Z = H或成盐阳离子的当量)。首选cpds。具有R 1 -R 5 = 1-2C烷基或烷氧基,Cl或CF 3; R 3也可以是OH或PhCH 2 O; Y = 1-2c烷基或苯基。取代由Cl; Z = H或等价物。 Na,K,Ca,Mg,Al,葡糖胺,N-甲基葡糖胺,单二或三乙醇胺或乙二胺
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