N-(heteroaryl-methyl)-7-acyl-6,14-(endoetheno or endoethano)- tetrahydro-nororipavines or-thebaines and salts thereof

摘要

Compounds of the formulaPPWHEREINP PR is hydrogen, methyl or acetyl,PPR.sub.1 is methyl, phenyl, or hydrogen,PPZ is --CH=CH-- or --CH.sub.2 --CH. sub.2 --, PPY is oxygen or sulfur, andP P R.sub.3 is hydrogen or methyl,PPAND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THEIR SALTS ARE USEFUL AS ANALGESICS AND ANTITUSSIVES.