method of therapeutically used vitamin a - happoamidien ready support.

摘要

1283887 Vitamin A acid amides F HOFFMANN-LA ROCHE & CO AG 19 April 1971 [2 Feb 1970] 20880/71 Heading C2V Vitamin A acid amides of formula where R and RSP1/SP are alkyl, alkyl substituted by alkoxy, alkyl substituted by dialkyl amino, hydroxy alkyl, phenyl or benzyl groups, are obtained by reacting Vitamin A acid or functional derivative thereof (e.g. an acid halide) with an amine of formula In examples there are prepared Vitamin A acid ethyl amide, methyl amide, isopropyl amide, butyl amide, methyl propyl amide, n-decyl amide, ethanol amide, phenyl amide, diphenyl amide, benzyl amide, 2-diethylamino-ethyl amide, 2-methoxy-ethyl amide, diethyl amide, di-(n-butyl) amide and di-(n-decyl) amide. The above-described Vitamin A acid amides may be formed into pharmaceutical preparations with the usual compatible carrier materials.