首页> 外国专利> method for preparation of car bonylfenylalkaancarbonzuren and its afgelei - links, the thus prepared carbonylfenylal - kaancarbonzuren and derived compounds.method for the preparation of compounds with pharmacological properties thus far and far - preparation were formed.

method for preparation of car bonylfenylalkaancarbonzuren and its afgelei - links, the thus prepared carbonylfenylal - kaancarbonzuren and derived compounds.method for the preparation of compounds with pharmacological properties thus far and far - preparation were formed.

机译:的方法,用于制备汽车苯磺酰基链烷烃和其链节的方法,由此制得的羰基链烷醛和衍生化合物。形成了目前为止具有药理学性质的化合物的制备方法。

摘要

Compounds of the formula: IMAGE wherein R represents hydrogen or an alkyl radical, R1 represents a hydroxy, amino or alkoxy radical or an alkylamino or dialkylamino group, the various alkyl radicals and the alkoxy radical being optionally substituted by a dialkylamino group, the alkyl radicals of the said dialkylamino groups optionally being linked together to form a heterocyclyl radical with 5 or 6 atoms in the ring, and A represents the thieno[2,3-b]thien-2-yl or thieno[3,2-b]thien-2-yl radical, the A-CO- grouping being attached to the 3- or 4-position of the phenyl ring, have been found to possess useful pharmacological properties and are particularly active as analgesics, antipyretics, agents for inhibiting platelet aggregation and as anti-inflammatory agents.
机译:式:的化合物,其中R代表氢或烷基,R1代表羟基,氨基或烷氧基或烷基氨基或二烷基氨基,各种烷基和烷氧基任选地被二烷基氨基取代,所述二烷基氨基的烷基任选地连接在一起以形成在环中具有5或6个原子的杂环基,并且A表示噻吩并[2,3-b]噻吩-2-基或噻吩并[3,2-b已经发现,A-CO-基团连接在苯环的3或4位上的] thien-2-yl基团具有有用的药理性质,并且特别用作镇痛药,退烧药,血小板抑制药聚集并用作抗炎药。

著录项

  • 公开/公告号NL7700656A

    专利类型

  • 公开/公告日1977-08-02

    原文格式PDF

  • 申请/专利权人 RHONE-POULENC INDUSTRIES TE PARIJS.;

    申请/专利号NL19770000656

  • 发明设计人

    申请日1977-01-21

  • 分类号A61K31/38;C07D495/04;

  • 国家 NL

  • 入库时间 2022-08-23 00:47:49

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