still for framstellning of intravenos's alternative - human immunoglobulin with natural half-life

摘要

1535977 Intravenou s immunoglobulins BIOTEST - SERUM - INSTITUT GmbH 21 May 1976 [18 June 1975] 21047/76 Heading A5B [Also in Division C3] Pharmaceutical compositions for intravenous administration comprise native human immunoglobulin with a natural half life and unchanged antibody activity in relation to human plasma or serum preferably free from anticomplementary activity prepared by heating human plasma or serum for a period of time 30 minutes to 4 hours at a temperature of from above 50 to 60‹C, followed by fractionation and preparation of a product suitable for intravenous administration together with a non-toxic pharmaceutically acceptable carrier or diluent.