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A procedure for the preparation of morphine compounds. (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of morphine compounds. (Machine-translation by Google Translate, not legally binding)
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机译:吗啡化合物的制备方法。 (通过Google翻译进行机器翻译,没有法律约束力)
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摘要
A procedure for the preparation of morpholine compounds of the formula: **(See formula)** where R1 is hydrogen or C1-C4 alkyl; R2 is hydrogen, C1-C4 alkyl, C3-C5 alkenyl/C3-C5 alkynyl/(C1-C4) arylalkyl, (C3-C6) cycloalkyl (C1-C4) alkyl, C2-C4 polyhaloalkyl or C2-C4 hydroxyalkyl; A is straight or branched C2-C4 alkylene; B is (see formula) are each 1,2-phenylene optionally substituted with one or more substituents selected from the group consisting of halogen, C1-C4 alkyl and C1-C4 alkoxy; and its non-toxic salts, the procedure of which is to react the tricyclic compound of the formula: **(See formula)** where B, C1 and C2 are those defined above, with the morpholinomethyl compound of the formula: **(See formula)** where X is a conventional leaving group and R1, R2 and A are as defined above. (Machine-translation by Google Translate, not legally binding)
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