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3-Thiomethyl-2(2-(dialkylamino)ethyl)indoles - useful as CNS depressants and antiaggresive agents
3-Thiomethyl-2(2-(dialkylamino)ethyl)indoles - useful as CNS depressants and antiaggresive agents
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机译:3-硫代甲基-2(2-(二烷基氨基)乙基)吲哚-可用作中枢神经系统抑制剂和抗凝剂
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摘要
Cpds. of formula (I) and their acid addn. salts (where R1, R2 and R3 are H or 1-7C alkyl; R4 is 1-7C alkyl, 6-10C aryl, aralkyl, or a 5-6 membered heterocyclic ring having 1 or 2 N, O or S; and R5 is H, 1-7C alkyl, alkoxy or OH), are useful as CNS depressants, e.g. when administered intraperitonially to rodents e.g. mice at a dose of 10-100 mg./kg., sedation is produced. (I) are also useful as mild sedatives or anti-aggression agents, and can be formulated with tablets or injections.
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