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《有机化学国际期刊(英文)》
>Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4#39;-yl)-1,2,4-Triazino5,6-ib/iIndole Moiety as Antifungal Agents
Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4#39;-yl)-1,2,4-Triazino5,6-ib/iIndole Moiety as Antifungal Agents
Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thiophenol and/or cycloaddition with thiolactic acids in nonpolar solvents. Structures of the products confirmed by elemental analysis and spectral measurements. The new systems obtained were evaluated as antifungal agents.
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