method for preparation of 9 - (3 - o - acyl - (beta) - d - arabinofuranosyl) adenineverbindin gene and 9 - (2,3 - di - o - acyl - (beta) - d - arabinofuranosyl) adenineverbindingen,method for the preparation of a pharmaceutical preparation with application and so formed a pharmaceutical preparation.

摘要

9-(3-O-Acyl- beta -D-arabinofuranosyl)adenine compounds, 9-(2,3-di-O-acyl- beta -D-arabinofuranosyl)adenine compounds, and their production by reacting in each case the corresponding 5-silyl ether derivative with a tetraalkylammonium fluoride. The compounds are useful as antiviral agents. The compounds are water-soluble and lipophilic, thereby being adaptable to a wide variety of pharmaceutical formulations.