still for framstellning of tri p-toluenesulfonate of s - adenosyl - l - methionine (sam)

摘要

The invention relates to the tri-p-toluensulphonate of S-adenosil-L-methionine, to the process for its preparation by addition of p-toluensulphonic acid in critical proportion to an aqueous solution containing S-adenosil-L-methionine, as well as to pharmaceutical compositions containing the new salt as the active principle, for use in numerous fields in humar therapy. The salt is an active ingredient in therapeutic compositions useful in the treatment of morbic affections wherein the metabolism of the lipids, of the glucids, of the protids, or of the catecholamines or of the biogene amines is primitively or secondarily altered.