SEEN TO PROMOTE NEW PIPERAZINES DISPOSED

摘要

Disubstituted piperazines of the formula: IMAGE wherein: IMAGE is naphthyl, benzo [b] furanyl, benzo [b] thienyl, benzodioxolyl, benzodioxanyl, benzodioxacycloheptanyl, coumaranyl, chromanyl, DELTA 3-chromenyl, thiochromanyl or DELTA 3-thiochromenyl, X is nitrogen and simultaneously Y is oxygen or sulfur, or X is sulfur, imino (NH) or methylimino (N CH3) and simultaneously Y is nitrogen, and R is hydrogen, lower alkyl, phenyl, halophenyl, lower-alkylphenyl or lower alkoxyphenyl. These compounds possess interesting pharmacological and therapeutic properties, and may be used as medicines, especially in the treatment of hypertension, peripheral vascular disorders and Parkinson's disease.