pharmaceutical composition for combating the flow of bile in the stomach

摘要

A solid pharmaceutical composition comprising anhydrous cholestyramine, 0.6 to 1.7 parts by weight of low viscosity grade alginic acid/sodium alginate per weight of cholestyramine, the low viscosity grade alginic acid/sodium alginate having 0 to 75% of the acid groups neutralized, 0.1 to 0.3 parts by weight of citric acid per weight of sodium alginate, and sufficient sodium carbonate or bicarbonate mixtures thereof to neutralize the acid groups of the alginic and citric acids. The compositions may be used in the treatment of conditions associated with duodeno-gastric reflux of bile into the stomach.