首页> 外国专利> Antipsoriasis monoethyl fumarate formulations - contg. polyethylene glycol, isopropyl myristate and/or isopropyl palmitate

Antipsoriasis monoethyl fumarate formulations - contg. polyethylene glycol, isopropyl myristate and/or isopropyl palmitate

机译:抗牛皮癣富马酸单乙酯制剂-续聚乙二醇,肉豆蔻酸异丙酯和/或棕榈酸异丙酯

摘要

New medicaments for the treatment of psoriasis vulgaris are based on fumaric acid monoethyl ester (I) and its mineral salts, and contain (a) polyethylene glycols which are water-soluble and which are liquid, melt at body temp. or are solid, (b) isopropyl myristate, which is fat-soluble and liquid, and/or (c) isopropyl palmitate, which is fat-soluble and melts at body temp. The use of (a), and (b) and/or (c) adjuvants gives preparations in which (I) and its mineral salts are stable and in which the adjuvants are not adversely affected by the active components. The active components may be present in the medicaments in dissolved form, and their release can be controlled. The preparations may be fat- or water-soluble.
机译:用于治疗寻常型牛皮癣的新药物是基于富马酸单乙酯(I)及其无机盐,并且包含(a)水溶性聚乙二醇,该聚乙二醇在人体温度下会熔化。或为固体,(b)脂溶性和液体的肉豆蔻酸异丙酯,和/或(c)脂溶性的并且在人体温度下融化的棕榈酸异丙酯。 (a),(b)和/或(c)佐剂的使用提供了这样的制剂,其中(I)及其矿物盐是稳定的,并且佐剂不受活性成分的不利影响。活性成分可以以溶解形式存在于药物中,并且可以控制它们的释放。制剂可以是脂溶性或水溶性的。

著录项

  • 公开/公告号DE2621214A1

    专利类型

  • 公开/公告日1977-11-17

    原文格式PDF

  • 申请/专利权人 KORONIS GMBHCHEMISCH-PHARMAZEUTISCHE PRAEPARATE;

    申请/专利号DE19762621214

  • 发明设计人

    申请日1976-05-13

  • 分类号A61K31/215;

  • 国家 DE

  • 入库时间 2022-08-22 22:02:37

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