Antibiotics am31alpha, am31beta and am31gamma and method for their preparation

摘要

Diaminoalditol derivs. (I) and diaminoalditol (II) and their acid addition salts are novel cpds. (where R = H or 1-12C alkanoyl). (I) are antibiotics active against gram-positive and gram-negative bacteria when administered parenterally e.g. in vivo activity in mice shows them to be effect against Escherichia coli, Salmonella typhosa and Klebsiella pneumoniae. MIC tests against a wide range of organisms are described.