首页> 外国专利> Antidepressant phenyl-pyridyl-amines - spec 3-(4-bromophenyl)-N-methyl-3-(3-pyridyl)-allylamine, by dehydrog.. 3-(4-bromophenyl)-3-hydroxy-N-methyl-3(3-pyridyl)-propylamine

Antidepressant phenyl-pyridyl-amines - spec 3-(4-bromophenyl)-N-methyl-3-(3-pyridyl)-allylamine, by dehydrog.. 3-(4-bromophenyl)-3-hydroxy-N-methyl-3(3-pyridyl)-propylamine

机译:抗抑郁药苯基吡啶胺-规格3-(4-溴苯基)-N-甲基-3-(3-吡啶基)-烯丙胺,通过脱氢处理.3-(4-溴苯基)-3-羟基-N-甲基- 3(3-吡啶基)-丙胺

摘要

3-(4-Bromophenyl)-N-methyl-3-(3-pyridyl)-allylamine (I), pref. in the form of the germoetric isomer (Ia), and its pharmaceutically tolerable salts are new. (I) is an antidepressant, as shown by inhibition of mouse brain 5-hydroxytryptamine and noradrenaline uptake in vitro and in vivo.
机译:3-(4-溴苯基)-N-甲基-3-(3-吡啶基)-烯丙胺(I),优选。以细菌异构体(Ia)形式存在,并且其可药用盐是新的。 (I)是抗抑郁药,如在体外和体内抑制小鼠脑5-羟色胺和去甲肾上腺素的摄取所显示。

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