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Method of selectively removing lipoprotein from blood plasma or serum using sulfated carbohydrate ion-exchangers
Method of selectively removing lipoprotein from blood plasma or serum using sulfated carbohydrate ion-exchangers
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机译:使用硫酸化碳水化合物离子交换剂从血浆或血清中选择性去除脂蛋白的方法
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摘要
The invention relates to the use of a sulphated ion exchanger to selectively remove lipoproteins from blood plasma or serum. Although the attraction between sulphate groups and proteins has long been recognized it has now unexpectedly been found that cationic ion exchangers whose ion exchange capacity is provided by sulphate groups bind lipoproteins selectively in presence of other plasma or serum proteins and ions when they are equilibrated with solutions containing divalent cations and the same cation is added to the plasma or serum. Types of ion exchanger matrices and applications of the utlity are discussed.
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