首页>
外国专利>
NOVEL PROSTANE DERIVATIVE * PRODUCTION THEREOF AND COMPOSITION HAVING PHARMACOLOGICAL AND VETERINARY CORPUS LETEUM CONTRACTING ACTION
NOVEL PROSTANE DERIVATIVE * PRODUCTION THEREOF AND COMPOSITION HAVING PHARMACOLOGICAL AND VETERINARY CORPUS LETEUM CONTRACTING ACTION
展开▼
机译:新型丙烷衍生物*具有药理学和兽医学意义的血脂收缩作用的生产及其成分
展开▼
页面导航
摘要
著录项
相似文献
摘要
Prostane derivs. of formula (I) are new. In the formula, the gp. (II) is of formula (III) to (VI); R1 is 1-10C opt. branched alkyl, alkoxyalkyl or haloalkyl, 1-6C omega-carboxyalkyl, phenyl or naphthyl opt. substd. by one or more halo, nitro phenyl, 1-5C alkyl, alkoxy or haloalkyl. R2-4 are each H or 1-5C alkyl; X is ethylene or trans-vinylene; Y is 1-6C alkyleneoxy where the O atom is bonded to R5, 1-6C alkylene or a direct bond; R5 is phenyl or naphthyl opt. substd. as above; n is 1-4; and m is 0 or 1. (I) possess high luteolytic activity and are therefore useful as contraceptives or for control of the oestrous cycle in animals. Some (I) also possess high activity in preventing blood platelet aggregation. (I) may be used to induce labour or early abortion, or as hypotensives for the relief of broncho-spasm or the inhibition of gastric acid production.
展开▼