UREAS, THIOUREAS AND GUANIDINES N,N'-DISUBSTITUTED BY HETEROCYCLO-ALKYLENE AND/OR HETEROCYCLO-ALKYLENETHIOALKYLENE GROUPS

摘要

The compounds are N,N'-substituted thioureas, ureas and guanidines which are H-2 histamine receptor inhibitors. Two compounds of this invention are N,N'-bis[2-((4-methyl-5-imidazolyl)methylthio)ethyl]thiourea and N,N'-bis[2-((4-methyl-5-imidazolyl)methylthio)ethyl]-N''-cyanoguanidin e.