首页> 外国专利> new benzeenpropanaminederivaten and their salts, their preparation, their application as medicines and pharmaceutical sectors - ceutische preparations containing them.

new benzeenpropanaminederivaten and their salts, their preparation, their application as medicines and pharmaceutical sectors - ceutische preparations containing them.

机译:新的苯丙丙烷胺衍生物及其盐,其制剂,在医药和制药领域的应用-包含它们的针灸制剂。

摘要

Novel benzene-propanamines of the formula IMAGE I' wherein X is selected from the group consisting of hydrogen, chlorine, fluorine and bromine, R1 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, R2 is alkyl of 1 to 5 carbon atoms, R3 is selected from the group consisting of hydrogen, chlorine, bromine, -CF3, methyl and methoxy when R4 is nitro and R3 is selected from the group consisting of amino and acetamido when R4 is hydrogen and their non-toxic, pharmaceutically acceptable acid addition salts having anorexigenic activity and inhibit serotonine uptake in vivo and in vitro and their preparation.
机译: I'的新型苯丙胺,其中X选自氢,氯,氟和溴,R1选自氢和1-5个碳原子的烷基,R2为烷基在1至5个碳原子中,当R4为硝基时,R3选自氢,氯,溴,-CF3,甲基和甲氧基;当R4为氢时,R3选自氨基和乙酰氨基具有麻醉作用的可吸收毒性的药学上可接受的酸加成盐,并在体内和体外抑制5-羟色胺的摄取及其制备方法。

著录项

  • 公开/公告号NL7901457A

    专利类型

  • 公开/公告日1979-08-28

    原文格式PDF

  • 申请/专利权人 ROUSSEL-UCLAF S.A. TE PARIJS.;

    申请/专利号NL19790001457

  • 发明设计人

    申请日1979-02-23

  • 分类号C07C93/00;C07C103/38;A61K31/135;A61K31/16;

  • 国家 NL

  • 入库时间 2022-08-22 20:40:50

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