2.9 -DICHLORO-6 -FLUORO-16 -METHYL-11 ,17 , 21-TRIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONES

摘要

2,9 alpha -Dichloro-6 alpha -fluoro-16 alpha -methyl-11 beta ,17,21-trihydroxy- pregna-1,4-diene-3,20-dione compounds of the formula (I) IMAGE (R1, R2 = OR where R = H, acid residue) have antiinflammatory effects. They are prepared by reacting corresponding 2-dechloro compounds with chlorine and subsequently eliminating HCl from the 1,2-dichloro compounds obtained in this way.