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AN IMPROVED METHOD OF PRODUCING INTRAVENOUSLY INJECTABLE GAMMA GLOBULIN
AN IMPROVED METHOD OF PRODUCING INTRAVENOUSLY INJECTABLE GAMMA GLOBULIN
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机译:静脉注射可伽玛球蛋白的生产方法的改进
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摘要
An improved process is provided for the preparation of a gamma globulin suitable for intravenous administration from the readily available Fraction II or II + III plasma protein paste or from the corresponding fractions originating from placental extracts. The Fraction II or II + III paste is extracted with water at a pH of 4.9 to 6.0 and impurities are fractionally precipitated by addition of polyethylene glycol to 4% of wt./vol. and then 6% vol. ethanol. The desired gamma globulin is then precipitated at a pH 8.0 by addition of polyethylene glycol to 12% wt./vol.
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