A procedure for the preparation of 3,20-dioxo-7-halo-4pregnenos and -1,4-pregnadienos. (Machine-translation by Google Translate, not legally binding)

摘要

A process for the preparation of 3,20-dioxo-7alpha-halo-4-pregnanes and -1,4-pregnadienes of the formula ** (formula) ** wherein the dashed line at positions 1,2 indicates a bond simple 1,2 or a double bond 1,2; w is a group (h, h), (h, lower alkyl), (h-alpha-ov1) or = cht, where v1 is a hydrogen atom or an acyl radical of retinoic acid or of a carboxylic acid having up to 12 carbon atoms, and t is a hydrogen atom, fluorine or chlorine or a lower alkyl group; q is a chlorine or bromine atom or an ov group in which v is a hydrogen atom or an acyl radical of a carboxylic acid having up to 12 carbon atoms, or, provided that w is a group (h, h) or (h, lower alkyl), q can also be a hydrogen atom; or else q and w taken together are a group 16 alpha, 17alpha-lower alkylidene-dioxy, -cycloalkylidenedioxy or -aralkohylidenedioxy together with a hydrogen atom in the 16beta position. (Machine-translation by Google Translate, not legally binding)