Derivatives of 1,3-dihydro-3-(1-(2-(2,3-dihydro-1,4-benzodioxin-2-yl)2-hydroxyethyl)piperidin-4-yl)2H-indol-2-on, process for their preparation, their use as medicaments and pharmaceutical compositions containing them

摘要

Novel derivatives of 1,3-dihydro 3- / 1- / 2- (2.3-dihydro-1,4-benzodioxin-2-yl) 2-hydroxy ethyl / piperidin-4-yl / 2H-indol 2-one, process for their preparation, their use as medicaments and pharmaceutical compositions containing them.; The invention relates to novel derivatives of 1,3-dihydro 3- / 1- / 2- (2.3-dihydro-1,4-benzodioxin-2-yl) 2-hydroxy ethyl / piperidin-4-yl / 2H -indol-2-one, process for their preparation, their use as medicaments and pharmaceutical compositions containing them.; The above derivatives of the formula: wherein Ri is hydrogen, chlorine, bromine, fluorine or alkoxy of 1 to 5 carbons, R ₂ is hydrogen or alkyl of 1 to 5 carbons, in racemic or optically active forms, as well as salts addition with mineral or organic acids.; The derivatives of the invention show a significant antihypertensive activity.