Benzimidazole - 2 - carbamic - derivatives, pharmaceutical compositions containing these compounds and their use in the combating para sita, thereby helminthoses

摘要

Benzimidazoles are provided having the structure IMAGE wherein R is lower alkyl or phenyl- lower alkyl and A is IMAGE wherein R1 is lower alkyl, R2 is hydrogen or lower alkyl, or R1 and R2 may be taken together with the carbons to which they are attached to form a cycloalkenyl ring, R3 is hydrogen or lower alkyl, and y is 0 or 1; IMAGE wherein R4 and R5 are the same or different and are hydrogen or lower alkyl, R6 is lower alkyl or phenyl, and R7 and R8 are the same or different and are chlorine, bromine, fluorine or iodine, m is 0 to 3, n is 0 to 3, and m+n is /=5; or IMAGE wherein R9, R10 and R11 may be the same or different and may be lower alkyl or lower alkoxy, z is 0, 1 or 2 and p is 1 to 5, with the proviso that when A is IMAGE R is lower alkyl. These compounds have anthelmintic properties.