Veterinary use of sodium cromoglycate and analogues - for treating and preventing allergic respiratory and gastrointestinal disorders

摘要

Prophylactic and curative treatment of allergic disorders in cats, dogs, pigs, horses and cattle comprises administering a cpd. having activity similar to that of sodium cromoglycate, esp. one of formula (I) or one of their salts (where X is a 3-7C polymethylene chain opt. substd. by OH). Cpds. are used for the relief or prevention of respiratory and pulmonary disorders, neonatal diarrhoea in pigs and calves etc. Pref. dose is 40-80 mg daily by inhalation in calves and pigs. For gastrointestinal disorders the oral dose is preferably 10-200 mg for pigs and 50-500 mg for cattle. For cats and dogs the daily dose is 25-250 mg orally. In an example, epidemic diarrhoea in calves was prevented by treating 10 calves with 100 mg/day of disodium cromoglycate in 100 ml of milk from birth to day 21.