PROCEDURE FOR THE FRAMSTATION OF 1,2,3-THIADIAZOLE-5-YL-URINEEMNEN

摘要

A process for the preparation of 1,2,3-thiadiazol-5-yl ureas of the general formula IMAGE I in which a 1,2,3-thiadiazol-5-carbohydroxam acid derivative of the formula IMAGE II is dissolved in an inert organic solvent with an acid halide of the formula R4-X III to form an acylated derivative which then reacts with an amine of the formula IMAGE V to form the desired product.