TOPICALLY ANTIINFLAMMATORY 4,4'-DIHYDROXY-3,3-TRIPHENYL METHANE DECARBOXYLIC ACID DERIVATIVES AND RELATED COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS

摘要

Pharmaceutical compositions, containing a 4,4'-dihydroxy-3,3'-triphenylmethanedicarboxylic acid(or an oxidised derivative) as active ingredient, are described and are prepared conventionally in a form suitable for topical administration e.g. ointment. The compositions are useful for the treatment of inflammatory diseases and inflammatory conditions of the skin. Many of the active ingredients are novel compounds. A representative novel active ingredient is 4"-cyano-4,4'-dihydroxy-5,5'-dimethyl-3,3'-triphenylmethanedicarboxylic acid.