2-(4-PHENYL-4-HYDROXYPIPERIDINOMETHYL) TETRALONE AND INDANONE COMPOUNDS

摘要

ABSTRACT OF THE DISCLOSURETetralone and indanone compounds of the formulawherein R1 is H, OH, alkoxy of 1-4 carbon atoms, cycloalkoxy of3-6 carbon atoms, F, Cl, Br, alkanoyloxy of 1-6 carbon atoms;R2 is OH or alkoxy of 1-4 carbon atoms or R1 and R2 collectivelyare methylenedioxy; R3 is H or CH3; Ar is phenyl or phenylsubstituted by up to 5 of alkyl of 1-4 carbon atoms, alkoxy of1-4 carbon atoms, F, Cl, Br or CF3; n is 1 or 2, and physiological-ly acceptable acid addition salts thereof, are central nervoussystem depressants. They may be prepared by certain specifiedand recited reactions of compounds containing the groupingorpracursions thereof.