2- (4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO 4.5 DECAN-8- YL)ALKYL -1H-BENZ DE ISOQUINOLIN-1,3 (2H)-DIONES

摘要

AbstractNew compounds, which exhibit antidepressantactivity and are also useful as antiinflammatory agents,have the following formulawherein R1 and R2 are independently selected from hydrogen,lower alkyl, lower alkoxy, lower alkylthio, halogen, tri-fluoromethyl, amino, nitro and cyano; R3 is selected fromhydrogen, lower alkyl and lower alkenyl; R4 is selectedfrom hydrogen, lower alkyl and halogen, and A is a straightor branched chain alkylene of 1 to 8 carbons; and a pharma-ceutically acceptable acid addition salt thereof.