Reducing agent for technetium - 99m and reduction process with the formation of with technetium labeled substances

摘要

Reductant compositions for reducing technetium to produce technetium labelled ligands comprise a substrate having attached thereto a reducing complex having sufficient redox potential to reduce technetium from the + 7 oxidation state. Preferably the reducing complex comprises a reducing agent for technetium and a chelating ligand therefor. Technetium labelled ligands are prepared by mixing such ligands with pertechnetate in the presence of the reductant of this invention and separating the reductant from the resulting labelled ligand. Technetium labelled ligands that are substantially free from reducing agent used in their preparation may be made in this manner.