3-Pyridyl-thiazoline-2-thione derivs of formula (I) are new In (I), (a) R1 is H, 1-2C alkyl or methoxymethyl, R2 is 1-2C alkyl in position 4,5 or 6 and R3 is methyl, or (b) R3 is H and R1 is H, 1-4C alkyl or 1-4C opt. branched alkoxy methyl and R2 is 1-4C alkyl in position 4,5 or 6 or R1 is cyclopropyl and R2 is H. (I) are anti-ulcer cpds which are active in rats at doses of 5-100 mg/kg p.o (Rossi and Shay tests) and in guinea pigs at the same dose levels (Anderson and Watt test). Oral LD50 N 100 mg/kg.
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机译：式（I）的3-吡啶基-噻唑啉-2-硫酮衍生物是新的在（I）中，（a）R 1为H，1-2C烷基或甲氧基甲基，R2为4,5或6位的1-2C烷基，并且R 3为甲基，或（b）R 3为H且R 1为H，1-4C烷基或1-4C opt。支链烷氧基甲基，R2为4,5或6位的1-4C烷基，或R1为环丙基，R2为H。（I）是抗溃疡药，在大鼠中的剂量为5-100 mg / kg po（罗西（Rossi）和谢伊（Shay）试验）和豚鼠在相同剂量水平下（安德森和瓦特试验）。口服LD50 N 100 mg / kg。
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