1 - Carboxymethyl - 5 - mercaptotetrazol, Application procedure, 7 - amino acid - 3 - 1 - Carboxymethyl - il - 5 - tetrazole thiomethyl - 3-cephem-4-carboxylic - carboxylic,Procedure for obtaining them and Procedure to obtain compounds of acid Acyl - 7 - 3 - Carboxymethyl - tetrazole thiomethyl - il - 5 - 3 - 4 - carboxylic cefem

摘要

Certain 7-acylamido-3-(1-carboxy-loweralkyl-tetrazol-5-ylthiomethyl)-3-cephem- 4-carboxylic acids and their salts and easily hydrolyzed esters of the 4-carboxyl group were synthesized and found to be potent antibacterial agents which exhibited good aqueous solubility. In a preferred embodiment the 7-substituent was 2'-aminomethylphenylacetamido.