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Antitussive and analgesic di:glaucine phosphate - having no unpleasant flavour, suitable for oral admin.
Antitussive and analgesic di:glaucine phosphate - having no unpleasant flavour, suitable for oral admin.
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机译:镇咳镇痛药二磷酸青草酯-无异味,适合口服。
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摘要
d-Glaucine phosphate (I) is new. It is an antitussive agent with an oral ED50 of 170.1 mg/kg and analgesic. Its lack of a bitter taste makes it much simpler to administer than the free alkaloid. (I) is prepd. by treating d-glaucine with at least 1/4 molar excess of phosphoric acid. This may be effected in an inert organic solvent such as acetone, ethanol, chloroform etc.
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