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PROCESS FOR THE PREPARATION OF PHARMACEUTICAL OR MEDICINAL TABLETS FOR ORAL ADMINISTRATION, WITH DELAYED DELIVERY OF ACTIVE ACTIVE, IN TABLETS IN WHICH THE QUANTITY OF RELEASE OF THE ACTIVE AGENT IS DEFAULT.
PROCESS FOR THE PREPARATION OF PHARMACEUTICAL OR MEDICINAL TABLETS FOR ORAL ADMINISTRATION, WITH DELAYED DELIVERY OF ACTIVE ACTIVE, IN TABLETS IN WHICH THE QUANTITY OF RELEASE OF THE ACTIVE AGENT IS DEFAULT.
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机译:在有效剂量释放量不合格的片剂中制备口服给药的药用或药用片剂的方法。
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摘要
A process for the preparation of matrix-type tablets with retarded liberation of the active agent. The liberation of the active agent from the tablets takes place at a speed that has been adjusted precisely in advance. In the granulation process, polymethacrylate plastics insoluble in neutral or slightly acid water either as dissolved in an organic solvent or as a water dispersion are used as the retarding matrix substance. Before the tablets are compressed, an ester of a large-molecule fatty acid or a product obtained from same by means of hydrogenation is mixed into the grain mix in order to adjust the rate of liberation of the active agent.
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