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Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions

机译:苯并二恶英羧酸衍生物,其制备及其在抑制脂肪形成的组合物中的作用

摘要

This invention relates to benzodioxincarboxylic acid derivatives.;There are provided benzodioxincarboxylic acid derivatives of general formulawherein R' is an alkoxy group of from 1 to4 carbon atoms or a 2-propenylamino group, and R, which is attached at the 6- or 7-position of the benzodioxin ring system, is a substituent selected from formyl, acetamido, (hydroxyimino)methyl, 1-(hydroxyimino)ethyl, (methoxyimino)methyl, 1-(methoxyimino)ethyl, -(hydroxyimino)benzyl, benzamido and 2-methyl-4-thiazolyl, processes for their preparation; lipogenesis inhibiting compositions containing them and the preparation of such compositions.;Benzodioxincarboxylic acid derivatives of general formula I have exhibited lipgenesis inhibiting activity.
机译:本发明涉及苯并二恶英羧酸衍生物。 <图像文件=“ IMGA0001.GIF” he =“ 22” id =“ ia01” imgContent =“ chem” imgFormat =“ GIF” inline =“ no” wi =“ 86” /> < [化学式]其中,R'为1-4个碳原子的烷氧基或2-丙烯基氨基,并且连接在苯并二恶英环系的6-或7-位上的R是选自甲酰基的取代基,乙酰胺基,(羟基亚氨基)甲基,1-(羟基亚氨基)乙基,(甲氧基亚氨基)甲基,1-(甲氧基亚氨基)乙基,-(羟基亚氨基)苄基,苯甲酰胺基和2-甲基-4-噻唑基。含有它们的脂肪生成抑制组合物及其制备方法;通式Ⅰ的苯并二恶英羧酸衍生物具有抑制脂肪生成的活性。

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