首页>
外国专利>
4-Tert.-butoxy-phenyl-glycine nitrile, and process for the preparation of D-(-)- and L-(+)-4-hydroxy-phenyl glycine
4-Tert.-butoxy-phenyl-glycine nitrile, and process for the preparation of D-(-)- and L-(+)-4-hydroxy-phenyl glycine
展开▼
机译:4-叔丁氧基苯基甘氨酸腈,以及制备D-(-)-和L-(+)-4-羟基苯基甘氨酸的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention relates to 4-tert-butoxyphenylglycine nitrile (I) IMAGE and a process for the preparation of D - (-) - 4-hydroxyphenylglycine (IIa) and L - (+) - 4-hydroxyphenylglycine (IIb) IMAGE by I is reacted in a manner known per se in alcoholic solution and in the presence of a carbonyl compound with approximately the equimolar amount of L - (+) - tartaric acid or D - (-) - tartaric acid and the D - (-) - obtained in crystalline form 1-L - (+) - tartrate or L - (+) - 1-D - (-) - tartrate at 20 to 110 ° C in acidic aqueous solution with elimination of the L - (+) - tartaric acid or the D - (-) - Tartaric acid, hydrolysis of the nitrile group and hydrolytic cleavage of the tert-butyl group converted into IIa or IIb.
展开▼