首页> 外国专利> New sulfonylhydrazones of 1,4 - dioxo - and 4 - oxoquinoxaline - 2 - carboxaldehyde and their application as agents antibacterial

New sulfonylhydrazones of 1,4 - dioxo - and 4 - oxoquinoxaline - 2 - carboxaldehyde and their application as agents antibacterial

机译:1,4-二氧代和4-氧喹喔啉-2-甲醛的新磺酰azo及其在抗菌剂中的应用。

摘要

The invention relates to novel chemical compounds which have useful antibacterial properties and are also of value in promoting animal growth and improving animal feed efficiency. More specifically, these new chemical compounds are certain sulfonylhydrazones of 1,4-dioxoquinoxaline-2-carboxaldehyde, 4-oxoquinoxaline-2-carboxaldehyde and certain derivatives thereof of formula (I): IMAGE (I) wherein A is N or N - O; R is a member selected from the group consisting of alkyl having from one to five carbon atoms, trifluoromethyl, phenyl, npahthyl, benzyl, styryl and phenyl substituted by up to two members selected from the group consisting of Cl, F, Br, CH3, CH3O and NO2; R1 is hydrogen or methyl; R2 is hydrogen or methyl; R3 is a 6- or 7-position substituent and is selected from the group H, Cl, CH3, CH3O, SO2NH2, SO2NHCH3 and SO2N(CH3)2; R4 is a 7- or 6-position substituent and is selected from the group H, Cl and CH3; with the proviso that when R4 is Cl or CH3, R3 and R4 are the same.
机译:本发明涉及具有有用的抗菌特性并且在促进动物生长和改善动物饲料效率方面也有价值的新型化合物。更具体地说,这些新化合物是1,4-二氧代喹喔啉-2-甲醛,4-氧代喹喔啉-2-甲醛的某些磺酰基hydr及其式(I)的某些衍生物:<图像>(I),其中A是N或N -> O; R是选自由具有一个至五个碳原子的烷基,三氟甲基,苯基,萘基,苄基,苯乙烯基和苯基所取代的成员,该取代基最多选自由Cl,F,Br,CH3, CH3O和NO2; R1是氢或甲基; R 2是氢或甲基; R 3是6或7位取代基,并且选自H,Cl,CH 3,CH 3 O,SO 2 NH 2,SO 2 NHCH 3和SO 2 N(CH 3)2; R4是7或6位取代基,并且选自H,Cl和CH3;前提是当R4为Cl或CH3时,R3和R4相同。

著录项

  • 公开/公告号FR2377388B1

    专利类型

  • 公开/公告日1981-02-27

    原文格式PDF

  • 申请/专利权人 PFIZER INC;

    申请/专利号FR19780001197

  • 发明设计人

    申请日1978-01-17

  • 分类号C07D241/52;A23K1/17;

  • 国家 FR

  • 入库时间 2022-08-22 15:06:41

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