首页> 外国专利> REMEDY FOR SUPERFICIAL MYCOSIS

REMEDY FOR SUPERFICIAL MYCOSIS

机译:过度真菌病的补救措施

摘要

PURPOSE:The titled remedy, consisting of a specific substituted naphthylmethyl propiolate as an active constituent, and having a slight acute toxicity without irritant action and making patients feed a pain in the coated affected part or giving out an offensive smell. CONSTITUTION:A remedy for the superficial mycosis containing a compound of formulaI(X is H, halogen or alkyl; Y is H or halogen; Z is H or alkyl), e.g. 1-naphthylmethyl propiolate, as an active constituent. The remedy as an alcoholic agent or lotion prepared by dissolving or dispersing the compound in a liquid carrier or an ointment prepared by mixing or adsorbing the compound in a solid carrier is applied to the affected part. The amount of the active constituent in the remedy is preferably 0.5-3wt%. The compound of formulaIis obtained by reacting a halogenomethylnaphthalene of formula II (A is halogen) with an alkali metallic propiolate of formula III (M is alkali metal) in the presence of an organic solvent.
机译:目的:标题为补救措施的药物,由一种特定的取代的丙酸萘基甲基丙酯作为活性成分组成,具有轻微的急性毒性而无刺激作用,使患者在被覆盖的患处感到疼痛或发出难闻的气味。组成:一种用于治疗表面真菌病的药物,该药物含有式I化合物(X为H,卤素或烷基; Y为H或卤素; Z为H或烷基),例如1-萘甲基丙酸酯,作为活性成分。通过将化合物溶解或分散在液体载体中而制备的作为酒精剂或洗剂的治疗剂或通过将化合物在固体载体中混合或吸附而制备的软膏剂应用于患处。药物中活性成分的量优选为0.5-3wt%。通过在有机溶剂的存在下,使式II的卤代甲基萘(A为卤素)与式III的碱金属丙酸酯(M为碱金属)反应而获得式I的化合物。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号