首页> 外国专利> PHARMACEUTICAL PREPARATION OF COMBINED AGENT OF SULFAMETHOXAZOLE AND TRIMETHOPRIM FOR MEDICATION THROUGH CELOM

PHARMACEUTICAL PREPARATION OF COMBINED AGENT OF SULFAMETHOXAZOLE AND TRIMETHOPRIM FOR MEDICATION THROUGH CELOM

机译:磺胺甲恶唑和三甲普利姆联合制剂的药理学研究

摘要

PURPOSE:A pharmaceutical preparation for medication through celom suppressing solidification tendency during blending, prolonging decomposition after molding, having quick absorption of agents and antimicrobial action, comprising sulfamethoxazole, trimethoprim, and phospholipid as active ingredients. CONSTITUTION:1-50mg/kg sulfamethoxazole (SMX) is blended with 1-5mg/kg trimethoprim (TMP), a small amount of, preferably 0.5-5wt% of phospholipid (e.g, phosphatidylcholine, phosphatidylethanolamine, etc.), and, if necessary, a base (e.g., peanut oil, coconut oil, ethylene glycol, etc.), a surface active agent to promote the absorption of the active ingredients, proper emulsifying agent, stabilizer, colorant, etc., to give a pharmaceutical preparation for medication through celom, having antimicrobial action.
机译:用途:一种以天麻为原料的药物制剂,以磺胺甲恶唑,甲氧苄啶和磷脂为有效成分,可抑制共混过程中的固化趋势,成型后的分解时间延长,具有快速的吸收剂和抗菌作用。组成:1-50mg / kg磺胺甲基异恶唑(SMX)与1-5mg / kg甲氧苄氨嘧啶(TMP),少量,优选0.5-5wt%的磷脂(例如,磷脂酰胆碱,磷脂酰乙醇胺等)混合,如果必要的基础剂(例如花生油,椰子油,乙二醇等),促进活性成分吸收的表面活性剂,适当的乳化剂,稳定剂,着色剂等,可制成用于通过天麻药,具有抗菌作用。

著录项

  • 公开/公告号JPS57109713A

    专利类型

  • 公开/公告日1982-07-08

    原文格式PDF

  • 申请/专利权人 SHIONOGI SEIYAKU KK;

    申请/专利号JP19800185780

  • 申请日1980-12-26

  • 分类号A61K9/02;A61K31/635;A61K47/12;A61K47/24;A61P31/04;

  • 国家 JP

  • 入库时间 2022-08-22 14:22:44

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