A pharmaceutical or veterinary composition for coelomic administration comprising sulfamethoxazole and trimethoprim with a base material(s), having a phospholipid included therein so that the tendency of solidification at the step of mixing of the said components in the manufacture of the said composition is prevented whilst solving the problem of delayed disintegration. When trimethoprim is used in the form of its salt or together with an organic acid in the manufacture of the said composition, the absorption rate of trimethoprim can be improved.
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