首页>
外国专利>
PEPTIDE INFLUENCING REPRODUCTION GLAND FUNCTION
PEPTIDE INFLUENCING REPRODUCTION GLAND FUNCTION
展开▼
机译:肽影响生殖腺功能
展开▼
页面导航
摘要
著录项
相似文献
摘要
LRF analogs having a modified D-Phe residue in the 6-position act as superagonists exhibiting potencies many times more than that of LRF. The peptides of their nontoxic salts can be administered by intravenous, subcutaneous, sublingual, oral, intravaginal, intranasal or rectal routes. The peptides can be used to regulate fertility in male and female mammals, including human beings. The peptides are represented by the following formula: p-Glu-His-Trp-Ser-Tyr-R1-Leu-Arg-Pro-NH-CH2-CH3 wherein R1 is selected from the group consisting of chloro-D-Phe, dichloro-D-Phe, methyl-D-Phe, nitro-D-Phe, acetylamino-D-Phe, methyoxy-D-Phe and pentamethyl-D-Phe.
展开▼